The Education Committee (EC) of the European Society for Organ Transplantation (ESOT) is a formally established committee of ESOT aiming to advance transplant education in Europe for all disciplines related to the field of transplantation.
The Basic Science Committee promotes scientific issues and transplantation research within ESOT. An active basic science community and an efficient translation of innovation into the clinic are crucial for the future of transplantation medicine.
The European Transplant Allied Healthcare Professionals (ETAHP) reaches out to allied healthcare professionals throughout Europe in order to ensure the best care possible for all transplant patients, with the aim to optimize patient outcomes.
The Young Professionals in Transplantation (YPT) is the Network for Junior Transplant professionals of ESOT, representing all young transplant clinicians and scientists who are beginning a career in transplantation and organ donation.
The mission of ECTORS is to provide a forum for discussing and stimulating novel developments in the fields of cellular therapies in organ transplantation, organ regeneration and generation of new organs from stem cells and biomaterials.
ECTTA is the forum for experience exchange on treatment of patients with end-stage heart and lung failure. Our aim is to improve outcomes for the patients.
EDTCO aims to support health care professionals to provide clinically effective programmes on organ and tissue donation, procurement and transplantation.
EKITA is the Organ Expert Section of ESOT on kidney transplantation in Europe, providing a forum for kidney transplantation professionals to exchange scientific information and views aimed at providing the best service to European patients .
The European Liver and Intestine Transplant Association (ELITA), previously known as the European Liver Transplant Association (ELTA), is a section of ESOT. Its membership represents the expertise on liver and intestinal transplantation in Europe.
ELPAT is a European platform that brings continuity and progress in European research and dialogue on "Ethical, Legal and Psychosocial Aspects of organ Transplantation". ELPAT currently consists of over 160 experts from more than 25 European countries.
EPITA is established to provide a forum for those working in the field of pancreas and islet of Langerhans transplantation or any other alternative form of beta cell replacement in Europe, to exchange scientific information and views related primarily to providing the best service for patients in Europe requiring pancreas or islet transplantation.
VCA has opened a new era in the field of transplantation, reconstructive and restorative surgery. This Section brings together 10 representatives of major European teams at the forefront in this field.
Welcome to the 11th EPITA Symposium and 40th AIDPIT Workshop!
The Symposium promotes engagement with clinicians, scientists and trainees across Europe who have expertise in pancreas and islet transplantation.
We will share new scientific developments and techniques amongst scientists in the field, and benchmark outcomes and results across European centres involved in clinical pancreas and islet transplantation.
The Symposium is the largest meeting in Europe where experts in the field of pancreas and islet transplantation can get together to share experience and outcomes. It is such a small niche area, and this meeting is critical to the working objectives of experts in the field.
Given the current circumstances, the Symposium will be presented as an online event.
This format offers a much broader global access to the event, and we look forward to welcoming new participants from the islet and pancreas community.
The 2-half day programme will include plenary sessions, oral abstract presentations and offer access to electronic posters.
This year, we are pleased to announce our patients inclusion initiative: a joint EPITA / EDTCO / ETAHP symposium.
SCIENTIFIC PROGRAMME (All times in Central European Time)
Monday 25 January, 2021
14:00 Welcome and introduction
Steve White, EPITA Chair – Newcastle upon Tyne, United Kingdom
14:00 – 15:00 Plenary session 1 – Marginal donors
Chairs: Torbjörn Lundgren, Stockholm, Sweden; Jon Odorico, Madison, United States
14:00 – 14:20 DCD pancreas transplantation in Spain – current status
Joana Ferrer, Barcelona, Spain
14:20 – 14:40 Expanding the donor pool with islets from DCD
Eelco de Koning, EPITA Past Chair, Leiden, The Netherlands
14:40 – 15:00 What are the limits of using paediatric donors for pancreas transplantation – risks and benefits
Fabio Vistoli, Pisa, Italy
15:00 – 15:15 Break
15:15 – 16:15 Parallel session 1: Oral presentations – Islet transplantation, basic science
Chairs:Valeria Sordi, Milan, Italy; Ekaterine Berishvili, Geneva Switzerland
15:15 – 15:25 OP01 ISLETS LOADED IN HYDROGEL DERIVED FROM HUMAN AMNIOTIC MEMBRANE (AMNIOGEL) REVERSE DIABETES IN IMMUNODEFICIENT MICE
Kevin Bellofatto, Geneva, Switzerland
15:25 – 15:35 OP02 DEVELOPMENT AND APPLICATION OF THE NEWCASTLE PANCREAS ENDOCRINE STRESS SCORE (NPESS) FOR ULTRASTRUCTURAL ASSESSMENT OF PANCREATIC ISLET CELLS
Nicola Dyson, Newcastle upon Tyne, United Kingdom
15:35 – 15:45 OP03 GLUCOSE DURING IN VITRO PANCREATIC BETA CELL REGENERATION: FRIEND OR FOE?
Chencheng Wang, Oslo, Norway
15:45 – 15:55 OP04 IMPROVING CD4+CD25+FOXP3+ TREG PERFORMANCES BY EX-VIVO EXPANSION IN THE PRESENCE OF IL-7 AND IL-15
Ilaria Cosorich, Milan, Italy
15:55 – 16:05 OP05 GENERATION OF Β CELLS FROM IPSC OF A MODY8 PATIENT WITH A NOVEL MUTATION IN THE CARBOXYL ESTER LIPASE (CEL) GENE
Silvia Pellegrini, Milan, Italy
16:05 – 16:15 OP06 TRANSPLANTATION SITE INFLUENCE ON ISLET CELLULAR COMPOSITION
Jan Kriz, Prague, Czech Republic
15:15 – 16:15 Parallel session 2: Oral presentations – Pancreas transplantation
Chairs: Claudia Bösmüller, Innsbruck, Austria; John Casey, Edinburgh, United Kingdom
15:15 – 15:25 OP07 IMPACT OF SARS-COV-2 ON INTERNATIONAL PANCREAS TRANSPLANT ACTIVITY
Sivesh Kathir Kamarajah, Newcastle upon Tyne, United Kingdom
15:25 – 15:35 OP08 PANCREAS TRANSPLANTATION DURING THE COVID-19 PANDEMIC. A SINGLE CENTRE’S EXPERIENCE
Ann Etohan Ogbemudia, Oxford, United Kingdom
15:35 – 15:45 OP09 IMPACT OF COVID-19 SELF-QUARANTINE MEASURES ON BEHAVIOUR, STRESS, ANXIETY AND GLYCAEMIC CONTROL IN PATIENTS WITH Β-CELL REPLACEMENT THERAPY
Cyril Landstra, Leiden, The Netherlands
15:45 – 15:55 OP10 NORMOTHERMIC REGIONAL PERFUSION INCREASES PANCREAS GRAFT UTILISATION AFTER DCD ORGAN DONATION
Aaron Hui, Edinburgh, United Kingdom
15:55 – 16:05 OP11 OUTCOMES OF SIMULTANEOUS PANCREAS-KIDNEY TRANSPLANTS FROM DONATION AFTER CIRCULATORY DEATH DONORS IN THE UK: A NATIONAL REGISTRY ANALYSIS
Chris Callaghan, London, United Kingdom
16:05 – 16:15 OP12 THE EFFECT OF DONOR DIABETES-ASSOCIATED GENOTYPES ON OUTCOMES AFTER PANCREAS TRANSPLANTATION
Charles Sneddon, Oxford, United Kingdom
16:15 – 16:30 Break
16:30 – 17:30 Plenary session 2 – 40th AIDPIT anniversary. 4 decades of beta cell replacement therapy and beyond
Chairs: Thierry Berney, Geneva, Switzerland; Steve White, Newcastle, United Kingdom
16:30 – 16:50 A “guided” tour in the future landscape of beta-cell based therapies for Type 1 Diabetes
Olle Korsgren, Uppsala, Sweden
16:50-17:10 Clinical islet transplantation-prevention of diabetic complications?
Paola Maffi, Milan, Italy
17:10 – 17:30 Pancreas preservation during the last four decades – what progress have we made?
Vassilios Papalois, ESOT President, London, United Kingdom
17:30 – 17:35 Break
17:35 – 17:55 EPITR UPDATE
Diego Cantarovich, Nantes, France
17:55 Closing remarks
Steve White, Newcastle upon Tyne, United Kingdom
Tuesday 26 January, 2021
14:00 Brief introduction
Julie Kerr-Conte, EPITA Vice-Chair, Lille, France
14:00 – 15:00 Plenary session 3 – Islets
Chairs: Eelco de Koning, Leiden, The Netherlands; Julie Kerr-Conte, Lille, France
14:00 – 14:20 Optimising beta cell function through islet mitochondrial transfer
Chloe Rackham, Exeter / London, United Kingdom
14:20 – 14:40 The effects of immunosuppression on islet function
Françoise Carlotti, Leiden, The Netherlands
14:40 – 15:00 Bioengineering pancreatic tissue
Francesca Spagnoli, London, United Kingdom
15:00 – 15:15 Break
15:15 – 16:15 Parallel session 3: Oral presentations – Islet transplantation, clinical
Chairs: Cyril Landstra, Leiden, The Netherlands; Jim Shaw, Newcastle upon Tyne, United Kingdom; Roger Lehmann, Switzerland
15:15 – 15:25 OP13 ISLET CELL ISOLATION AND TRANSPLANTATION FROM DCD DONORS IN SCOTLAND
Andrew Sutherland, Edinburgh, United Kingdom
15:25 – 15:35 OP14 LINEAR RELATION BETWEEN PRIMARY ISLET GRAFT FUNCTION AND 5-YEAR OUTCOME OF IT: A SINGLE CENTER RETROSPECTIVE COHORT STUDY IN 39 PATIENTS
Mikael Chetboun, Lille, France
15:35 – 15:45 OP15 ISLET TRANSPLANT OUTCOMES IN THE INTEGRATED UK PROGRAMME
Claire Counter, Bristol, United Kingdom
15:45 – 15:55 OP16 SALVAGING A PANCREATIC ALLOGRAFT FOR ISLET ALLO-AUTOTRANSPLANTATION
Maarten Tol, Leiden, The Netherlands
15:55 – 16:05 OP17 IMPACT OF HLA DONOR SPECIFIC ANTIBODIES IN THE ERA OF CELL THERAPY: CLINICAL TRAJECTORIES IN ISLET TRANSPLANTATION ILLUSTRATE A CHALLENGING MODEL
Mehdi Maanaoui, Lille, France
16:05 – 16:15 OP18 COGNITIVE IMPACT OF IMMUNOSUPPRESSIVE TREATMENTS AFTER ISLET TRANSPLANTATION: A CASE-CONTROL STUDY
Aurélie Mailliez, Lille France
15:15 – 16:15 Parallel session 4: Oral presentations – Pancreas transplantation
Chairs: Sanjay Sinha, Oxford, United Kingdom; Rainer Gruessner, New York, United States
15:15 – 15:25 OP19 IMPACT OF INSULIN THERAPY IN PANCREAS TRANSPLANTATION DONORS ON GRAFT OUTCOMES: AN ANALYSIS OF THE OPTN/UNOS DATABASE
Pedro Ventura-Aguiar, Barcelona, Spain
15:25 – 15:35 OP20 DEVELOPMENT OF EX VIVO NORMOTHERMIC PERFUSION AS AN INNOVATIVE METHOD TO ASSESS PANCREASES AFTER PRESERVATION
Ann Etohan Ogbemudia, Oxford, United Kingdom
15:35 – 15:45 OP21 POST-TRANSPLANT MALIGNANCIES AFTER SIMULTANEOUS PANCREAS KIDNEY TRANSPLANTATION: IMPLICATIONS ON LONG-TERM OUTCOME FROM A SINGLE-CENTER PERSPECTIVE
Felix Julius Krendl, Innsbruck, Austria
15:45 – 15:55 OP22 PANCREAS TRANSPLANTATION IN BLACK ASIAN AND ETHNIC MINORITIES- A SINGLE CENTRE EXPERIENCE IN THE UK
Jeevan Prakash Gopal, London, United Kingdom
15:55 – 16:05 OP23 LIVE OXYGENATION MONITORING DURING HYPOTHERMIC OXYGENATED PERFUSION (HOPE) ON PANCREAS: A PRECLINICAL FEASIBILITY EVALUATION
Benoît Mesnard, Nantes, France
16:05 – 16:15 OP24 UNEXPLAINED FEVER AFTER PANCREAS TRANSPLANTATION: CHARACTERISTICS AND LONG-TERM OUTCOMES
16:15 – 16:30 Break
16:30 – 17:30 Debate: National pancreas allocation policies should include both islet and pancreas transplant recipients
Chairs: Joana Ferrer, Barcelona, Spain; Fabio Vistoli, Pisa, Italy
Paul Johnson, Oxford, United Kingdom
Helmut Arbogast, Munich, Germany
17:30 – 17:35 Break
17:35 – 19:05 Patients inclusion initiative Joint EPITA / EDTCO / ETAHP symposium
Chairs: Alessandra Grossi, Varese, Italy; Nichon Jansen, Leiden, The Netherlands
17:35 – 18:05 Life on the waiting list
David Paredes-Zapata, EDTCO Past Chair, Barcelona, Spain
Pablo Ferrer Ben Amar, Barcelona, Spain
18:05 – 18:35 Fear of losing my transplant
Anna Forsberg, ETAHP Chair, Lund, Sweden
18:35 – 19:05 25 years of assessing patients for TPIAT – a clinical nurse specialist’s perspective
Cris Pollard, Leicester, United Kingdom
19:05 Closing remarks and presentation of awards
Julie Kerr-Conte, Lille, France; Steve White, Newcastle, United Kingdom
Steve White, EPITA Chair
Julie Kerr-Conte, EPITA Vice-Chair
Claudia Bosmüller, EPITA Board member
Joana Ferrer, EPITA Board member
Artur Kwiatkowski, EPITA Board member
Valeria Sordi, EPITA Board member
Fabio Vistoli, EPITA Board member
Eelco de Koning, EPITA Past Chair
“The 11th EPITA Symposium & 40th AIDPIT Workshop, Virtual, Italy, 25/01/2021-26/01/2021 has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) with 7 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.”
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